Genetics

Researchers develop a tool to predict which tumour patients will benefit from immunotherapy

Scientists have built an algorithm that detects genetic mutations that activate the immune system, facilitating the identification of cancer patients more prone to benefit from immunotherapy European researchers have developed an algorithm that identifies genetic alterations that trigger the immune system, helping distinguish which cancer patients are more likely to benefit from immunotherapy. This algorithm also predicts which people affected by hereditary diseases may profit from treatments with commercially available medications. Genetic alterations can perturb protein synthesis, sometimes leading to the formation of truncated proteins which do not operate as expected. Known as nonsense mutations, these types of modifications can give …

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